Biology I (BIO 106)

Tribhuvan University

Institute of Science and Technology

Bachelor of Science in Computer Science and Information Technology

Course Title: Biology I

Course no: BIO-106                                                                                     Full Marks: 60+20+20

Credit hours: 3                                                                                               Pass Marks: 24+8+8

Nature of course: Theory (3 Hrs.) + Lab (3 Hrs.)

Course Synopsis: Living System and their properties, major biological molecules, basic physiological processes, introduction of genetics, basic concepts of diversity and evolution.

Goal: The course is aimed at providing the introduction of biological system with respect to nature, behavior and functioning of the cell.

Course Contents:

Unit 1.                                                                                                             5 Hrs.

1.1    Introduction: Brief introduction to all aspects of Biology

1.2    Bio-molecular: Carbohydrates, Lipids, Proteins and Nucleic acid

Unit 2.                                                                                                             19 Hrs.

2.1    Cell structure and functions: Cell theory, cell membrane, transport system across the membrane, organelles composed of membranes, nonmenbranous organelles, nuclear components and major cell types

2.2    Enzymes: Nomenclature, biocatalysis, action of enzymes, environmental factors, co-enzymes, enzyme activation and inhibition.

2.3    Biochemical Pathways: Introduction, cellular respiration, glycolysis, TCA Cycle, ETC, ATP calculation, fermentation, protein and fat metabolism, photosynthesis-C3 and C4 pathways, photorespiration, chemosynthesis, transpiration.

Unit 3.                                                                                                               7 Hrs.

3.1    Genetics: Laws of inheritance, linkage and crossing over

3.2    Diversity within species: Gene pool concept, genetic variety, role of natural selection in evolution, factors influencing natural selection, Hardy-Weinberg equilibrium concept and application

Unit 4.                                                                                                                6 Hrs.

4.1    Material exchange in the body: Basic principle, blood circulation, pulmonary and systemic, nature of blood and role of heart, gas exchange, respiratory anatomy, lung function, digestive system, kidney structure and function

Unit 5.                                                                                                                8 Hrs.

5.1    Body's control mechanism: Nerve impulse, synapse, CNS organization, endocrine system, sensory input and output coordination

5.2    Immune system: Defense mechanism, humeral and cell mediated immune responses, vaccines and monoclonal antibody.

Laboratory Works:

• Identification of biomolecules: cellulose, Lignin, Lipid, Protein.
• Analysis of amino acids in protein by paper chromatography and paper electrophoresis.
• Separation of photo synthetic pigments by paper chromatography.
• Determination of value of RQ of different respiratory substrates.
• Study of different types of plant and anima cells in temporary preparation.

Text Books:

E.D. Enger & F.C. Ross, Concepts in Biology, 9th Edition, Tata McGraw Hill

Reference Book:

P.H. Reven et.al, Biology, 5th Ed. WBC McGraw Hill.